Medical Sciences
OPEN ACCESS
Pharmacological Activity Of The Possessing New Atypical Neuroleptics 1-Phenyltetrahydroisoquinoline Structure
DOI
Crossref DOI
10.37547/TAJMSPR/Volume02Issue08-03
tajmspr
2020
VOL. 2
/ NO. 08
AUGUST
RESEARCH OVERVIEW
Abstract
The first synthesized derivative of (3¢,4¢-methylenedioxyphenyl) -6,7-methylenedioxy-1,2,3,4-
tetrahydroquinoline, conventionally designated F-29, showed neuroleptic properties - they have
hypothermic, cataleptogenic, less pronounced suppression of motor activity, lack of central αadreno- and M-anticholinergic action and less toxic in severity comparable to the activity of a more
close analogue of the neuroleptic haloperidol, which has motor and autonomic disorders [1], which F29 lacks
RESEARCH TOPICS
Keywords
Neuroleptic activity,
catalepsy,
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