An Integrated Public Health Framework For Advancing Early Breast Cancer Detection, Risk Reduction, And Preventive Care Through Population-Based Strategies

Breast cancer remains one of the most significant public health challenges worldwide, accounting for substantial morbidity, mortality, and socioeconomic burden across both developed and developing countries. Despite remarkable advances in diagnostic technologies and therapeutic interventions, disparities in screening accessibility, preventive healthcare delivery, health literacy, and policy implementation continue to limit improvements in early detection and patient survival. Recent epidemiological evidence indicates that the global burden of breast cancer is expected to increase considerably over the coming decades, emphasizing the urgent need for integrated population-based strategies capable of addressing both biological and health system determinants simultaneously (Arnold et al., 2022). Consequently, public health approaches have evolved beyond disease treatment toward comprehensive frameworks that emphasize prevention, risk assessment, organized screening, community engagement, policy support, and equitable healthcare access.

This review article develops an integrated public health framework for advancing early breast cancer detection, risk reduction, and preventive care by synthesizing evidence from existing literature. The study critically evaluates global epidemiological trends, current screening practices, healthcare inequalities, preventive interventions, policy initiatives, and emerging perspectives on population-level cancer control. Particular attention is given to the interaction between behavioral, environmental, biological, nutritional, and healthcare system factors influencing breast cancer outcomes. Furthermore, the review examines how coordinated public health infrastructures can improve screening participation, facilitate timely diagnosis, reduce healthcare disparities, and strengthen long-term survivorship care.

The proposed framework integrates primary prevention, organized screening programs, community education, policy development, multidisciplinary healthcare collaboration, digital surveillance, and continuous quality improvement into a unified model capable of supporting sustainable breast cancer control strategies. The review demonstrates that effective public health interventions require coordinated actions across healthcare providers, policymakers, researchers, and community organizations rather than isolated clinical efforts. The findings suggest that strengthening preventive healthcare systems, expanding equitable screening services, promoting evidence-based policy implementation, and integrating risk-based population management can substantially improve early diagnosis while reducing disease burden globally. The proposed framework offers practical guidance for future research, healthcare planning, and public health policy aimed at achieving comprehensive breast cancer prevention and control.

Breast cancer, Public health framework, Early detection, Cancer prevention, Risk reduction

Arnold M, Morgan E, Rumgay H, Mafra A, Singh D, Laversanne M, Vignat J, Gralow JR, Cardoso F, Siesling S, Soerjomataram I. Current and future burden of breast cancer: Global statistics for 2020 and 2040. Breast. 2022;66:15-23. PMid:36084384 PMCid:PMC9465273.

Bradley CJ, Kitchen S, Bhatia S, Bynum J, Darien G, Lichtenfeld JL, Oyer R, Shulman LN, Sheldon LK. Policies and Practices to Address Cancer's Long-Term Adverse Consequences. J Natl Cancer Inst. 2022;114(8):1065.

Espina C, Soerjomataram I, Forman D, Martín-Moreno JM. Cancer prevention policy in the EU: Best practices are now well recognised; no reason for countries to lag behind. J Cancer Policy. 2018;18:40-51.

Gbenonsi GY, Martini J, Mahieu C. An analytical framework for breast cancer public policies in Sub-Saharan Africa: results from a comprehensive literature review and an adapted policy Delphi. BMC Public Health. 2024;24(1):1535.

Lei S, Zheng R, Zhang S, Wang S, Chen R, Sun K, Zeng H, Zhou J, Wei W. Global patterns of breast cancer incidence and mortality: A population-based cancer registry data analysis from 2000 to 2020. Cancer Commun (Lond). 2021;41(11):1183-1194.

Obeagu EI. N2 Neutrophils and Tumor Progression in Breast Cancer: Molecular Pathways and Implications. Breast Cancer (Dove Medical Press). 2025;17:639-651.

Obeagu EI. The nutritional equation: decoding diet's influence on breast cancer risk and progression - a perspective. Ann Med Surg (Lond). 2025;87(9):5528-5534.

Obeagu EI. The selenium paradox friend or foe in breast cancer? Ann Med Surg (Lond). 2025;87(9):5569-5577.

Obeagu EI, Obeagu GU. Exploring neutrophil functionality in breast cancer progression: A review. Medicine. 2024;103(13):e37654.

Obeagu EI, Obeagu GU. Exploring the profound link: Breastfeeding's impact on alleviating the burden of breast cancer - A review. Medicine. 2024;103(15):e37695.

Obeagu EI, Obeagu GU. Lymphocyte infiltration in breast cancer: A promising prognostic indicator. Medicine. 2024;103(49):e40845.

Obeagu EI, Isiko I. N1 and N2 Neutrophils in Breast Cancer: Mechanisms, Clinical Relevance, and Therapeutic Potential. International Journal of Medical Sciences and Pharma Research. 2025;11(2):1-11.

Obeagu EI, Isiko I. N1 and N2 Neutrophil Polarization in Breast Cancer: Predictive Value for Treatment Outcomes. International Journal of Medical Sciences and Pharma Research. 2025;11(2):12-20.

Ponce-Chazarri L, Ponce-Blandón JA, Immordino P, Giordano A, Morales F. Barriers to Breast Cancer-Screening Adherence in Vulnerable Populations. Cancers (Basel). 2023;15(3):604.

Shetty MK. Screening for breast cancer with mammography: current status and an overview. Indian J Surg Oncol. 2010;1(3):218-223.

Wheeler SB, Reeder-Hayes KE, Carey LA. Disparities in breast cancer treatment and outcomes: biological, social, and health system determinants and opportunities for research. Oncologist. 2013;18(9):986-993.