Medical Science | Open Access | DOI: https://doi.org/10.37547/tajmspr/Volume08Issue05-16

Role Of Fetuin-A In The Clinical And Laboratory Manifestations Of Calcification In Chronic Kidney Disease

Yuldoshev Turgun Ravshanovich , Termiz Branch of Tashkent State Medical University, Uzbekistan
Sabirov Maksud Atabaevich , Republican Center of Specialized Nephrology and Kidney Transplantation Scientific and Practical Medicine, Uzbekistan
Munavvarov Burkhan Abdujalilovich , Tashkent State Medical University, Uzbekistan

Abstract

The article presents the results of a study on changes in calcium-phosphorus balance in patients with chronic kidney disease, depending on the level of fetuin-A in the blood serum, and on the calcification processes that occur in the body. It also discusses changes in calcium, phosphorus, PTH, and vitamin D, as well as the occurrence of cardiac calcification, in the study groups with normal and low levels of fetuin-A. The conclusions based on the conducted studies also recognize the promising research that needs to be done in this regard.

Keywords

Chronic kidney disease, fetuin-A, calcium

References

Esayan A.M. i dr. Prevalence of chronic kidney disease among patients, obrativshikhsya v uchrejdeniya primary medical-sanitary assistant. резолаты проспективного наблюдательного issledovaniya v 12 regionax Rossii // Nephrology (volume 13) No. 3. 2021. S 6 - 16. DOI : https://dx.doi.org/10.18565/nephrology.2021.3.6-16

Isirgapova S.N. and head q. Effect of blood electrolyte disturbances on quality of life in young climacteric patients of SBK stage 5. // Scientific report , educational , spiritual journal of Tibbiyotdayangi Kun . Bukhara. - 2023. - No. 8. - Pages 90-98 .

Isirgapova S.N. i dr. Disturbance of mineral exchange in patients with climacteric syndrome receiving programmatic hemodialysis and ego correction // Materialy kongressa natsionalnogo pochechnogo fonda respubliki Kazakhstan: "VAJNAYa VEXA: konceptualnye pokhody i klyuchevye napravleniya mnogogrannoy nephrologii" Kazakhstan. Almaty. - 2022- S. 24-25.

Makhieva A.T. i dr. Fetuin A is a marker for early risk development of mineralo-osteoarthritis and cardiac-vascular formation. calcification in patients with chronic lung disease 5 - stage. Nephrology . 2022;26(4):105-109. https://doi.org/10.36485/1561-6274-2022-26-4-105-109

Papichev E.V. i dr. Fetuin-A. novyy hepatokin and diagnosis of rheumatoid arthritis. Clinical laboratory diagnostics. 2018; 63 (12): 756-760. DOI: http://dx.doi.org/10.18821/0869-2084-2018-63-12-756-760

Harman H. et al. Comparison of fetuin-A and transforming growth factor beta 1 levels in patients with spondyloarthropathies and rheumatoid arthritis. Int J Rheum Dis. 2016;20(12):2020-7. doi: 10/1111/1756-185X.12791.

Mihai S. et al. (2016). Proteomic biomarkers panel: new insights in chronic kidney disease. Dis . Markers 2016:3185232. doi : 10.1155/2016/3185232

Ozturk S. et al. Fetuin-A and its association with disease activity on psoriatic arthritis. Ann Rheum Dis. 2014;73:207. doi: 10.1136/annrheumdis-2014-eular.4473.

Pal D. et al. (20 2 2). Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance. Nat . Med . 18, 1279–1285. doi : 10.1038/nm.2851 .

Pedro Magalhães et al. Urinary fetuin-A peptides as a new marker for impaired kidney function in patients with type 2 diabetes, Clinical Kidney Journal, 2020, sfaa176.

Pedro Magalhães et al. Urinary fetuin-A peptides as a new marker for impaired kidney function in patients with type 2 diabetes, Clinical Kidney Journal, 2020, sfaa176.

Zhou Z. et al. (2019) Circulating Fetuin-A and Risk of All-Cause Mortality in Patients With Chronic Kidney Disease: A Systematic Review and Meta-Analysis. Front . Physiol . 10:966. https://doi.org/10.3389/fphys.2019.00966

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Yuldoshev Turgun Ravshanovich, Sabirov Maksud Atabaevich, & Munavvarov Burkhan Abdujalilovich. (2026). Role Of Fetuin-A In The Clinical And Laboratory Manifestations Of Calcification In Chronic Kidney Disease. The American Journal of Medical Sciences and Pharmaceutical Research, 8(05), 75–78. https://doi.org/10.37547/tajmspr/Volume08Issue05-16