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Family Case of The Clinical Course of Cartagener's Syndrome in Children

Shamsiyeva Eleonora Rinatovna
Associate Professor, Department of Children’s Diseases, Tashkent Medical Academy, Tashkent, Uzbekistan
DOI Crossref DOI 10.37547/tajmspr/Volume07Issue03-07
tajmspr 2025
VOL. 7 / NO. 03 MARCH
FULL TEXT PP. 43-45
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VOLUME 7
ISSUE 03
YEAR 2025
PAGES 43-45
RESEARCH OVERVIEW

Abstract

Kartagener's syndrome (KS) is a rare hereditary disease characterized by a triad of symptoms: primary ciliary dyskinesia, situs inversus, and chronic respiratory infections. This article presents a family case of KS in children, emphasizing the clinical features, diagnostic challenges, and management strategies. The study analyzes the genetic aspects, pathophysiology, and progression of the disease in affected siblings. Special attention is given to respiratory complications, recurrent infections, and the impact on the quality of life. Early diagnosis and comprehensive therapeutic approaches, including airway clearance techniques and antibiotic prophylaxis, are crucial for improving long-term outcomes in children with KS.

RESEARCH TOPICS

Keywords

Kartagener syndrome situs inversus primary ciliary insufficiency

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