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Medical Science OPEN ACCESS

EXPLORING THE APOPTOTIC EFFECTS OF ETHANOLIC EXTRACTS FROM HEXALOBUS MONOPETALUS LEAVES ON CERVICAL CANCER IN WISTAR RATS

Bertin Sezan
Laboratory of Biomembranes and Signalling Cell, University of Abomey-Calavi, Benin
Tiburce Alphonse
Laboratory of Biomembranes and Signalling Cell, University of Abomey-Calavi, Benin
tajmspr 2024
VOL. 6 / NO. 02 FEBRUARY
VOLUME 6
ISSUE 02
YEAR 2024
PAGES 09-15

Abstract

This study investigates the apoptotic effects of ethanolic extracts derived from Hexalobus Monopetalus leaves on cervical cancer in Wistar rats. Cervical cancer remains a significant health concern globally, necessitating the exploration of novel therapeutic agents. Hexalobus Monopetalus, a plant from the Annonaceae family, has exhibited promising pharmacological properties. The ethanolic extracts from its leaves are evaluated for their potential apoptotic effects on cervical cancer cells in an animal model. Through histopathological examination, biochemical assays, and molecular analyses, the study elucidates the apoptotic mechanisms underlying the anticancer activity of Hexalobus Monopetalus extracts, offering insights into their therapeutic potential for cervical cancer treatment.

Keywords

Hexalobus Monopetalus Annonaceae Ethanolic extracts

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