Medical Science
OPEN ACCESS
Coordination Iron And Copper Compounds In Medicine
DOI
Crossref DOI
10.37547/tajmspr/Volume08Issue02-08
tajmspr
2026
VOL. 8
/ NO. 2
FEBRUARY
RESEARCH OVERVIEW
Abstract
This article examines the role of iron and copper coordination compounds in modern medicine and pharmacology as of 2026. It substantiates the need to transition from inorganic metal salts to complex compounds with organic ligands to increase bioavailability and reduce toxicity. The mechanisms of action of modern drugs, including ferroptosis and cuproptosis , are described, as well as the use of metal complexes in the treatment of anemia, oncology, diagnostics (MRI and PET-CT), and regenerative medicine. Particular attention is paid to innovative delivery technologies, such as liposomal formulations and the use of AI in compound modeling.
RESEARCH TOPICS
Keywords
Coordination compounds
pharmacology
ferroptosis
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References
- Alimkhodzhaeva NT, Yuldashev NM, Akbarkhodzhaeva Kh.N ., Tadjieva H. Medicinal chemistry. – URI: http://repository.tma.uz/xmlui/handle/1/1461 - 2021
- Alimkhodzhaeva N.T. Biochemistry of Microelements. Tashkent, 2024.
- Akhmedov H.H., Khidoyatov BH Medicinal chemistry. – Tashkent: Fan, 2020. – 456 p.
- Leninger A.L. Fundamentals of Biochemistry. – M.: Mir, 2018. – 1248 p.
- Smith J. et al. Coordination Chemistry in Modern Medicine // Journal of Inorganic Biochemistry, 2025.
- Ivanov I.I. Innovative methods of anemia treatment. Moscow: Medicine, 2026.
- Proceedings of the International Conference on Metallodrugs . Tashkent , 2025.