MONITORING OF CEREBRAL PERFUSION PRESSURE IN PATIENTS WITH ACUTE ISCHEMIC STROKE
Abstract
we studied patients with ischemic stroke with antihypertensive medication for high arterial hypertension.
Material and methods: we studied 28 patients in the general intensive care unit of multidisciplinary TMA with acute cerebral ischemia syndrome caused by ischemic-type ACCD. The age of the patients was on average 61±7 years. There were 20 males and 8 females. The level of consciousness was assessed using the Glasgow scale. It ranged from 4 to 10 points.
Results: the given data clearly indicate a more pronounced decrease of SBP, DBP, ICP during intravenous infusion of Tahiben at the stages of the study. A significant difference in the duration of drug effects in the studied groups was noted. Thus, when using Tahiben, the target level of SBP and DBP could be maintained up to 220±54 minutes, while in the standard treatment group it was maintained for 68±8 minutes.
Conclusions: intravenous administration of Tahiben (urapidil) at the early hospital stage in patients with arterial hypertension against the background of standard baseline therapy of ACCD is an effective and safe method of urgent therapy, providing dosage BP reduction by 15-25% of the initial one.
Keywords
Downloads
References
- Ke-Qiong Yan, Qi-Si Wu. et.all. Blood Pressure Variability May Be a New Predictor for the Occurrence and Prognosis of Ischemic Stroke. Chinese MedicalSciences Journal Volume 38, Issue 3, September 2023, Pages 242-249
- Mursalov I., Muneer A. et.all. Managing high blood pressure in hypertensive patients with an acute ischemic stroke. Hipertensión y Riesgo Vascular Volume 39, Issue 4, October-December 2022, Pages 157-166
- Bruce M., Deborah B. et.all. Clinical Policy: Critical Issues in the Management of Adult Patients Presenting to the Emergency Department with Acute Ischemic Stroke. Annals of Emergency Medicine Volume 82, Issue 2, August 2023, Pages e17-e64
- Ricardo R., Blanca F. et.all. Management of acute ischemic strokeAbordaje y tratamiento del ictus isquémico en la fase aguda. Medicina Clínica (English Edition) Volume 161, Issue 11, December 7, 2023, Pages 485-492
- Natasha P. Appraisal of Clinical Practice Guideline: 2018 Guidelines for the Early Management of Patients with Acute Ischemic Stroke. Journal of Physiotherapy Volume 64, Issue 3, July 2018, Page 199
- Castillo J., Leira R. et al. Blood pressure decrease during the acute phase of ischemic stroke is associated with brain injury and poor stroke outcome. Stroke. - 2004.- Vol.35- P. 520-527.