Efficiency Of Intra-Articular Administration In Early Osteoarthrosis
Abstract
The purpose of this study was to investigate the function of knee joints in patients with early osteoarthritis (OA, according to the criteria of the American rheumatology Association 2010) stage I-III using visual analogue scale (VAS) for pain intensity and treatment outcomes, Lequesne index, expert indicators, samples of 4 meter walk to assess the effectiveness of intra-articular injection Hyaluronic Chondro. 80 patients aged 28 to 55 years were examined. The treatment regimen included recommendations from the European rheumatology League (EULAR, 2016) and Russia (Nasonov E. L., 2017). The results of therapy were evaluated in two groups. The first group included 43 patients who received Hyaluronic Chondro in the form of intra-articular injections, the second-37 patients who received chondroprotectors inside or in the form of intramuscular injections. Conclusion. Intra-articular administration of the drug Chondrogard has a positive clinical effect in early stage II-III OA with moderate impairment of knee joint function. The course of treatment should last at least 2 months
Keywords
Downloads
References
- Alekseeva L. I., taskina E. A., Kashevarova N. G. Osteoarthritis: epidemiology, classification, risk factors and progression, clinic, diagnosis, treatment. // Modern rheumatology. 2019. No. 13 (2). pp. 9-21.
- Anikin S. G. the Use of high-molecular hyaluronic acid preparations in the treatment of osteoarthritis. // Modern rheumatology. 2017. No. 11 (1). pp. 62-65.
- Anikin S. G., Kashevarova N. G., Korotkova T. A., etc. Evaluation of the efficacy, tolerability and safety of intra-articular administration of hyaluronic acid in patients with knee osteoarthritis. // Modern rheumatology. 2017. No. 11 (3). pp. 58-63.
- Belyaeva I. B., Lila a.m., Mazurov V. I., Raimuev K. V. Algorithm of pharmacological treatment of knee osteoarthritis (recommendations of ESCEO-2016). // Rheumatology, traumatology and orthopedics. 2017. No. 2. pp. 8-13.
- Benevolenskaya L. I., Brzezovsky M. M. Epidemiology of rheumatic diseases. Moscow, 2012. 237 p.
- Denisov L. N., Platova A. I., Menshikova I. V., Lila a.m. Osteoarthritis-aspects of pharmacotherapy. // Modern rheumatology. 2018. No. 2. pp. 97-102.
- Diagnosis and treatment of certain forms of rheumatic diseases from the position of evidence-based medicine. Educational and methodological guide. S. K. Adzhigaytkanova. M., GBOU VPO RNIMU named after N. I. Pirogov, 2013. 52 p.
- Kabalyk M. A. Textural characteristics of subchondral bone in osteoarthritis. // Kazan medical journal. 2016; Vol. 97. no. 4. pp. 518-523.
- Karataev A. E., Lila a.m. Osteoarthritis: modern clinical concept and some promising therapeutic approaches. // Scientific and practical rheumatology. 2018. No. 56 (1). pp. 70-81.
- karateev A. E. the Problem of musculoskeletal pain: what is interesting for a practicing doctor? Data from a survey of 846 Russian doctors. // Modern rheumatology. 2019. No. 13 (2). pp. 126-129.