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Molecular Genetic Factors Of Breast Cancer Development (Review)

Abdulla Nusratillayevich Abdukhakimov, Muqaddas Tukhtabievna Tukhtaboeva
Tashkent Regional Branch Of The Republican Specialized Scientific And Practical Medical Center Of Oncology And Radiology, Tashkent, Uzbekistan
DOI Crossref DOI 10.37547/TAJMSPR/Volume02Issue07-14
tajmspr 2020
VOL. 2 / NO. 07 JULY
FULL TEXT PP. 112-116
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VOLUME 2
ISSUE 07
YEAR 2020
PAGES 112-116
RESEARCH OVERVIEW

Abstract

The problem of timely detection of breast cancer is not only in its asymptomatic
development, but also in the absence of reliable diagnostic markers that contribute to the
early detection of the neoplastic process. The main objectives of oncogenomics are to
study the molecular mechanisms of carcinogenesis and develop optimal methods for
preventing, diagnosing and monitoring cancer. One approach to solving this problem is to
analyze the epigenetic characteristics of the tumor genome.

RESEARCH TOPICS

Keywords

: breast cancer heredity

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References

  1. Vanyushin B.F. Epigenetics today and tomorrow // Vavilov Journal of Genetics and
  2. Selection. - 2013. - No. 17 (4/2). - S. 805-832. 12
  3. Imyanitov E.N., Hanson K.P. Molecular Oncology: Clinical Aspects. - St. Petersburg,
  4. .-- 211 p. 4
  5. Kazubskaya TP, Loginov V.I., Khodyrev D.S., Ermilova V.D., Payanidi Yu.G.,
  6. Chkhikvadze N.V., Selchuk V.Yu., Braga E.A. Methylation of genes RASSF1A, RARβ2,
  7. SEMA3B in epithelial tumors of the mammary gland, ovaries and polyneoplasia // Tumors
  8. of the female reproductive system. - 2012. - No. 1. - S.61-68. 6
  9. Kazubskaya T.P., Khodyrev D.S., Pronina I.V., Ermilova V.D., Payanidi Yu.G.,
  10. Chkhikvadze N.V., Selchuk V.Yu., Braga E.A., Loginov V.I. Methylation of suppressor
  11. genes in epithelial tumors of the mammary gland and ovaries, including primary multiple
  12. // Russian Biotherapeutic Journal. - 2012. - No. 1. - Volume 11. - P.69-74.-3
  13. Laptiev SA, Korzhenevskaya MA, Imyanitov EN Molecular genetic "portrait" of breast
  14. cancer. Scientific notes of St. acad. I.P. Pavlova. 2017; 24 (2): 12-22. DOI: 10.24884 /
  15. -4181-2017-24-2-12-22.