Assessment of Risk and Prevention of Chronic Kidney Disease in Patients with Comorbid Conditions
Kayumov Nodrbek Ulug`bekovich , PhD, Assistant, Department of Internal Medicine, Nephrology and Hemodialysis, Tashkent State Medical University, UzbekistanAbstract
The study included 126 patients with comorbid conditions and risk factors for chronic kidney disease. The mean age of the patients was 59.3 ± 8.7 years. Arterial hypertension was observed in 96 patients, diabetes mellitus in 62 patients, cardiovascular diseases in 54 patients, and obesity in 47 patients. A decrease in estimated glomerular filtration rate below 60 ml/min/1.73 m² was detected in 39 patients, while albuminuria was found in 58 patients. A high and very high risk of chronic kidney disease progression was identified in 51 patients.The proposed prevention algorithm included regular monitoring of eGFR, albuminuria, blood pressure, glycemic status, lipid profile, body mass index, lifestyle correction, and elimination of nephrotoxic risk factors. The results indicate that patients with arterial hypertension, diabetes mellitus, obesity, and cardiovascular diseases require systematic screening and multidisciplinary follow-up. The use of an integrated risk assessment algorithm may contribute to early detection of renal dysfunction and prevention of chronic kidney disease progression in patients with comorbid pathology.
Keywords
Chronic kidney disease, comorbid conditions, arterial hypertension
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