Medical Science
OPEN ACCESS
Characteristics of The Health of Children with Down Syndrome, Taking into Account Vitamin D and Trace Element Status, Development of Methodological Approaches to Correction
DOI
Crossref DOI
10.37547/tajmspr/Volume08Issue02-23
tajmspr
2026
VOL. 8
/ NO. 2
FEBRUARY
RESEARCH OVERVIEW
Abstract
This article provides a comprehensive analysis of the health of children with Down syndrome, taking into account vitamin D levels and trace element status, as well as the development of scientifically based methodological approaches to correcting the identified disorders. Based on data from clinical trials conducted in 2015–2024.
Conclusions. A new vibration method for removing intracerebral hematomas is proposed. Further accumulation of clinical material and determination of indications for the use of the device and method are necessary.
RESEARCH TOPICS
Keywords
Vitamin D
trace elements
osteopenia
Downloads
Download data is not yet available.
SOURCES & SCHOLARSHIP
References
- World Health Organization. Genetic disorders and congenital anomalies: WHO report. - Geneva: WHO, 2022. - 214 p.
- Baranov A. A., Namazova-Baranova L. S. Children’s nutrition. - M.: GEOTAR-Media, 2020. - 512 p.
- Gromova O. A., Torshin I. Yu. Vitamin D and children’s health. — M.: Practical Medicine, 2019. — 304 p.
- Korovina N. A., Zakharova I. N., Dmitrieva Yu. A. Vitamin D deficiency in children and adolescents // Pediatrics. - 2021. - T. 100, No. 4. - P. 45–52.
- Litvinova N. A., Baranova E. A. Microelement status in pediatric practice. - St. Petersburg. : SpetsLit, 2018. - 286 p.
- Namazova-Baranova L. S., Kulichenko T. V. Immune disorders in children with chromosomal abnormalities // Russian Pediatric Journal. — 2020. — No. 5. — pp. 12–18.
- Aghajafari F., Field C. J., Kaplan B. J. et al. Vitamin D deficiency and Down syndrome: a systematic review // Pediatrics. — 2019. — Vol. 144, No. 3. — P. 1–12.
- Cashman K. D., Dowling K. G., Škrabáková Z. et al. Vitamin D deficiency in Europe // American Journal of Clinical Nutrition. — 2016. — Vol. 103, No. 4. — P. 1033–1044.
- Choi J., Park S., Kim J. Micronutrient imbalance in children with Down syndrome // Journal of Pediatric Endocrinology. — 2021. — Vol. 34, No. 7. — P. 875–883.
- Holick M. F. Vitamin D: physiology, molecular biology, and clinical applications. — New York : Springer, 2018. — 425 p.
- Kleszczyński K., Fischer T. Oxidative stress and Down syndrome // Free Radical Biology & Medicine. — 2020. — Vol. 152. — P. 341–350.
- Mithal A., Wahl D. A., Bonjour J. P. et al. Global vitamin D status // Osteoporosis International. — 2019. — Vol. 30, No. 1. — P. 1–10.
- Murray J., Ryan-Krause P. Obesity and micronutrient deficiency in children with Down syndrome // Journal of Pediatric Nursing. — 2022. — Vol. 62. — P. 45–52.
- Zachariah J. P., Johnson P. K. Bone health in Down syndrome // Bone Reports. — 2023. — Vol. 18. — P. 101–109.
- Petrenko Yu. V., Savelyeva N. V. Endocrine disorders in Down syndrome. - M.: Medicine, 2021. - 198 p.