Medical Science
| Open Access |
DOI: Acute Pancreatitis And Cationic Trypsinogen Gene Polymorphism In The Uzbek Population
Ismailov Uktam Safaevich , Department of Surgical Diseases No. 1, Tashkent State Medical University, Uzbekistan Madatov Kurbonboy Aminboevich , Department of Surgical Diseases No. 1, Tashkent State Medical University, Uzbekistan Matmuratov Seyilkhon Kuronboevich , Department of Surgical Diseases No. 1, Tashkent State Medical University, Uzbekistan Sharopov Asliddin Nasriddinovich , Department of Surgical Diseases No. 1, Tashkent State Medical University, Uzbekistan Rakhimov Rasulbek Ibrokhimovich , Department of Surgical Diseases No. 1, Tashkent State Medical University, UzbekistanAbstract
This article examines the impact of the Arg122His polymorphism in the PRSS1 gene on the incidence of acute pancreatitis. In the mechanism of acute pancreatitis development, environmental factors play an important role alongside genetic factors. Ethnic differences in the frequency distribution of alleles and genotypes of this gene's polymorphic variant were identified. Further advancement of molecular genetic research through studying the genetic basis of pancreatitis is crucial for developing new diagnostic methods and determining treatment strategies with an individualized approach to each patient.
Keywords
Acute pancreatitis, cationic trypsinogen (PRSS1), gene polymorphism
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Copyright (c) 2026 Ismailov Uktam Safaevich, Madatov Kurbonboy Aminboevich, Matmuratov Seyilkhon Kuronboevich, Sharopov Asliddin Nasriddinovich, Rakhimov Rasulbek Ibrokhimovich
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