Medical Science
| Open Access |
DOI: Laparoscopic Adrenalectomy In The Management Of Adrenal Neoplasms: Clinical Outcomes And Diagnostic Considerations
Omonov Oybek Avazxonovich , Republican Specialized Scientific and Practical Medical Center for Endocrinology named after Academician Y.H. Turakulov, Tashkent, Uzbekistan Muzaffarov Farrukh Umarovich , Republican Specialized Scientific and Practical Medical Center for Endocrinology named after Academician Y.H. Turakulov, Tashkent, Uzbekistan Mardonov Jamshid Normurotovich , Tashkent State Medical University, Tashkent, Uzbekistan State Institution “Republican Specialized Scientific and Practical Medical Center of Surgery named after Academician V.V. Vakhidov”, Tashkent, UzbekistanAbstract
Adrenal neoplasms represent a diagnostically and therapeutically challenging group of endocrine disorders. The introduction of minimally invasive surgical techniques and modern imaging modalities has significantly improved treatment outcomes; however, optimal patient selection and perioperative management remain critical factors influencing surgical success. Objective. To evaluate the clinical effectiveness and safety of laparoscopic adrenalectomy based on a prospective analysis of diagnostic and surgical outcomes in patients with adrenal neoplasms. Methods. A prospective clinical study included 125 patients with adrenal tumors examined between 2024 and 2025. Diagnostic evaluation consisted of hormonal assessment and multidetector computed tomography (MDCT) angiography with three-dimensional reconstruction. Laparoscopic adrenalectomy was performed in 50 patients. Clinical, hormonal, and morphological outcomes were analyzed, including postoperative recovery and complications. Results. Hormonally active tumors were identified in 78% of operated patients. Laparoscopic adrenalectomy was successfully completed in all cases without conversion to open surgery. Postoperative recovery was characterized by early mobilization and short hospitalization (5–7 days). Restoration of hormonal function occurred within 3–30 days in 96% of patients, while lifelong hormone replacement therapy was required in 4%. Histological examination revealed pheochromocytoma in 44%, ACTH-independent Cushing’s syndrome in 30%, aldosteroma in 16%, and adrenocortical adenomas in 10% of cases. Conclusions. Laparoscopic adrenalectomy is a safe and highly effective method for the treatment of adrenal neoplasms. Early diagnosis using modern imaging techniques combined with multidisciplinary perioperative management significantly improves clinical outcomes and reduces postoperative complications.
Keywords
Adrenal neoplasms, laparoscopic adrenalectomy, minimally invasive surgery
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