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DOI: Main Role Of Morphogenetic Between Fgf-23 And Sklotho In The Development Of Herdic And Vasicular Models In Chronic Key Disease Patients
Nodira Mirshavkatovna Alikhanova , Doctor Of Medical Sciences, Republican Scientific-Practical Medical Center Of Endocrinology Of The Ministry Of Health Of The Republic Of Uzbekistan Aikhojaeva Mokhira Akmalovna , Candidate Of Medical Sciences, Republican Scientific-Practical Medical Center Of Endocrinology Of The Ministry Of Health Of The Republic Of Uzbekistan Nazarova Nozimakhon Sunnatilla Kizi , 1 Year Basic Doctoral Student, Republican Scientific-Practical Medical Center Of Endocrinology Of The Ministry Of Health Of The Republic Of Uzbekistan Charos Bakhtiyorovna Musakhanova , Endocrinologist In The Department Of Diabetic Nephropathy, Republican Scientific-Practical Medical Center Of Endocrinology Of The Ministry Of Health Of The Republic Of UzbekistanAbstract
Diabetes is a major cause of chronic kidney disease (CKD). Poor blood sugar control accelerates the progression of CKD to terminal renal failure. Chronic kidney disease is also an important co-morbidity of diabetes. Impaired renal function further increases the risk of cardiovascular events in diabetic patients and ultimately carries a severe social and economic burden. Altered fibroblast growth factor 23 (FGF-23) and Klotho levels are considered the earliest biochemical abnormality of chronic kidney disease, the mineral and bone disease syndrome.
Keywords
Cardiovascular disease, chronic kidney disease
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