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Electrospun Nanofibrous Materials in Medicine and Cosmetology: Functional Requirements, Application Map and Polymer Selection Criteria

Shohruxmirzo Mahsudov
Namangan State Technical University, Namangan, Uzbekistan
Sherzod Korabayev
Namangan State Technical University, Namangan, Uzbekistan
Fayzulla Bekchanov
Kimyo International University in Tashkent, Tashkent, Uzbekistan
Ogabek Zaripov
Namangan State Technical University, Namangan, Uzbekistan
DOI Crossref DOI 10.37547/tajiir/Volume08Issue10-03
tajiir 2026
VOL. 8 / NO. 10 OCTOBER
FULL TEXT PP. 29-37
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VOLUME 8
ISSUE 10
YEAR 2026
PAGES 29-37
RESEARCH OVERVIEW

Abstract

Non-woven nanofibrous materials produced by electrospinning are increasingly used in wound management, tissue engineering, controlled drug delivery and cosmetic products. Although the number of reported formulations grows rapidly, the link between the intended clinical or cosmetic function and the material properties that must be engineered to achieve it is rarely stated explicitly, which makes polymer selection largely empirical. This review organises the reported evidence into a function–property–polymer map. Four application groups are analysed: therapeutic dressings, cell substrates for tissue engineering, drug-delivery matrices and cosmetic delivery films. For each group the governing material properties are identified — inter-fibre porosity and specific surface area, fibre diameter and its distribution, fibre orientation, degradation rate and its controllability, surface chemistry and residual-solvent toxicity. It is shown that fibre diameter and degradation controllability are the two properties that appear in all four application groups, whereas fibre orientation is decisive only for anisotropic tissue constructs. On this basis a set of selection criteria is proposed, and silk fibroin is identified as the natural fibre-forming polymer that satisfies the largest number of criteria simultaneously, principally because its degradation rate can be tuned through the β-sheet content without changing the polymer chemistry. The limitations of the current evidence base — the scarcity of quantitative structure–function correlations and of residual-solvent reporting — are discussed.

RESEARCH TOPICS

Keywords

Electrospinning nanofibrous material wound dressing

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