HIV SEROCONVERSION IN SERODISCORDANT COUPLES: INSIGHTS FROM A MALAYSIAN CONTEXT SEROCONVERSION
Mardiyah Azmi , University Sains Malaysia, Kubang Kerian, Kelantan, MalaysiaAbstract
Serodiscordant couples, where one partner is HIV-positive and the other is HIV-negative, face unique challenges and risks in terms of HIV transmission and seroconversion. This study aims to provide insights into HIV seroconversion in serodiscordant couples within the context of Malaysia. A retrospective analysis was conducted, utilizing data from medical records and interviews with serodiscordant couples attending HIV clinics in Malaysia. The study examines the factors associated with HIV seroconversion, including sexual behaviors, adherence to antiretroviral therapy (ART), and access to preventive measures. The findings shed light on the challenges faced by serodiscordant couples in Malaysia and provide valuable information for the development of targeted interventions and support services.
Keywords
seroconversion, antiretroviral therapy (ART), sexual behaviors
References
S. Colombe et al., “HIV-seroconversion among HIV-1 serodiscordant married couples in Tanzania: A cohort study,” BMC Infect. Dis., vol. 19, no. 1, pp. 1–8, 2019.
K. Curran, J. M. Baeten, T. J. Coates, A. Kurth, N. R. Mugo, and C. Celum, “HIV-1 prevention for HIV-1 serodiscordant couples,” Curr. HIV/AIDS Rep., vol. 9, no. 2, pp. 160–170, Jun. 2012.
E. Habte et al., “Predictors of HIV serodiscordance among couples in Southwestern Ethiopia,” Int. Assoc. Provid. AIDS Care, vol. 14, no. 3, pp. 234–240, 2015.
R. R. Yang, X. Gui, Y. Xiong, S. C. Gao, and Y. J. Yan, “Five-year follow-up observation of HIV prevalence in serodiscordant couples,” Int. J. Infect. Dis., vol. 33, pp. e179–e184, 2015.
M. S. Cohen, M. K. Smith, K. E. Muessig, T. B. Hallett, K. A. Powers, and A. D. Kashuba, “Antiretroviral treatment of HIV-1 prevents transmission of HIV-1: where do we go from here?,” Lancet, vol. 382, no. 9903, pp. 1–20.
M. S. Cohen, M. Mccauley, and T. R. Gamble, “HIV treatment as prevention and HPTN 052,” Curr Opin HIV AIDS2, vol. 7, no. 2, pp. 99–105.
M. Nasarruddin, W. M. Z. W. Mohammad, N. H. N. Hussain, S. H. Ali, and H. M. Zubir, “HIV-related characteristics among female partners of injecting drug users in Kelantan, Malaysia: A descriptive study,” AIDS Care - Psychol. Socio-Medical Asp. AIDS/HIV, vol. 27, no. 3, pp. 301–306, 2015.
K. Quarraisha, S. Seneziwe, and B. Cheryl, “Preventing HIV infection in women - a global health imperative!,” Clin Infect Dis, vol. 50, no. Suppl 3, pp. S122–S129.
S. Attia, M. Egger, and M. Mu, “Sexual transmission of HIV according to viral load and antiretroviral therapy : systematic review and,” AIDS, vol. 23, pp. 1397–1404, 2009.
L. Wang et al., “HIV seroconversion and prevalence rates in heterosexual discordant couples in China: A systematic review and meta-analysis,” AIDS Care - Psychol. Socio-Medical Asp. AIDS/HIV, vol. 24, no. 9, pp. 1059–1070, 2012.
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