★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★★Open research. Global perspectives.
editor@theamericanjournals.comPublisher Home ↗
Applied Sciences OPEN ACCESS

Advanced Surface-Enhanced Raman Spectroscopy and Nanobiosensor Technologies For Ultra-Sensitive Detection of Chemical Contaminants in Food Systems

Ananya R. Mehta
Department of Chemical and Biomolecular Engineering, University of Melbourne, Australia
tajas 2026
VOL. 8 / NO. 2 FEBRUARY
FULL TEXT PP. 88-91
DOWNLOAD PDF

View all articles in this issue ↗

VOLUME 8
ISSUE 2
YEAR 2026
PAGES 88-91
RESEARCH OVERVIEW

Abstract

The increasing prevalence of chemical contaminants in food systems, including heavy metals and pesticide residues, necessitates the development of highly sensitive, rapid, and reliable detection technologies. This research article provides a comprehensive and integrative analysis of advanced nanotechnology-driven sensing systems, with a primary focus on surface-enhanced Raman spectroscopy (SERS) and nanobiosensor platforms. Drawing exclusively from the provided references, the study evaluates the theoretical foundations, material innovations, detection mechanisms, and practical applications of nanosensors in food safety. The methodology employs a qualitative synthesis of interdisciplinary research encompassing nanomaterials, spectroscopy, biosensing, and green analytical chemistry. The findings reveal that SERS-based detection systems, particularly those utilizing hybrid nanostructures such as Au@AgPt nanoparticles, graphene composites, and nanorod arrays, demonstrate exceptional sensitivity and selectivity for detecting trace levels of heavy metals and pesticide residues. Additionally, emerging nanomaterials such as MXenes and organic chemical nanosensors offer novel pathways for enhanced signal transduction and multifunctional sensing. The integration of nanobiosensors with environmentally sustainable sample preparation techniques further enhances analytical efficiency while reducing ecological impact. However, challenges related to reproducibility, standardization, and real-world implementation remain significant. The discussion explores the broader implications of these technologies for food safety, regulatory frameworks, and public health, emphasizing the need for interdisciplinary collaboration and innovation. The study concludes that the convergence of SERS technology, nanobiosensing, and green analytical approaches represents a transformative paradigm for ensuring food safety in complex and globalized food systems.

RESEARCH TOPICS

Keywords

SERS nanobiosensors food safety pesticide detection

Downloads

Download data is not yet available.
SOURCES & SCHOLARSHIP

References

  1. Agarwal, R., Harini, P., Sri Varshni, J. (2025). New Insights on Nano Biosensors Applications for Chemical and Adulterant in Foods. In: Sillu, D., Bey Hing, G., Akhtar, N. (eds) Nanobiosensors for the Food Industry. Smart Nanomaterials Technology. Springer, Singapore. https://doi.org/10.1007/978-981-95-0136-6_9
  2. Dong T, Lin L, He Y, Nie P, Qu F, Xiao S (2018) Density functional theory analysis of deltamethrin and its determination in strawberry by surface enhanced Raman spectroscopy. Molecules
  3. El-Maghrabey RN, Garg D, Singh D, Sharma R, Verma N, Bhari R, Asadnia M (2022) Applications of nanomaterials for greener food analysis
  4. He Q, Han Y, Huang Y, Gao J, Gao Y, Han L, Zhang Y (2021) Reusable dual-enhancement SERS sensor based on graphene and hybrid nanostructures for ultrasensitive lead detection. Sensors and Actuators B Chemical
  5. Hsueh TJ, Ding RY (2022) A room temperature ZnO-NPs MEMS ammonia gas sensor. Nanomaterials
  6. Hu H, Wang N, Liao J, Tovar-Lopez FJ (2023) Recent progress in micro and nanotechnology enabled sensors for biomedical and environmental challenges. Sensors
  7. Jiao T, Hassan MM, Zhu J, Ali S, Ahmad W, Wang J, Lv C, Chen Q, Li H (2020) Quantification of deltamethrin residues in wheat by Ag@ZnO nanofibers based SERS. Food Chemistry
  8. Krishnamoorthy K, Manivannan G, Kim SJ (2012) Antibacterial activity of MgO nanoparticles based on lipid peroxidation. Journal of Nanoparticle Research
  9. Li L, Wang T, Zhong Y (2024) A review of nanomaterials for biosensing applications. Journal of Materials Chemistry B
  10. Liu C, Wang S, Dong X, Huang Q (2022) Flexible and transparent SERS substrates composed of Au Ag nanorod arrays for in situ detection of pesticide residues. Chemosensors
  11. Ly NH, Nguyen TH, Nghi ND, Kim Y, Joo S (2019) Surface enhanced Raman scattering detection of fipronil pesticide adsorbed on silver nanoparticles. Sensors
  12. Mahmoud ZH, Salman HK, Hussein HH (2023) Organic chemical nanosensors synthesis properties and applications. Brazilian Journal of Biology
  13. Pang S, Yang T, He L (2016) Review of SERS detection of synthetic chemical pesticides. Trends in Analytical Chemistry
  14. Sharma HR, Verma N, Singh M, Asadnia M (2022) Application of nanomaterials for greener sample extraction
  15. Song C, Li J, Sun Y, Jiang X, Zhang J, Dong C, Wang L (2020) Colorimetric and SERS dual mode detection of mercury ion via SERS active nanoparticles. Sensors and Actuators B Chemical
  16. Sreejith S, Ajayan J, Radhika JM (2024) Recent advances in nano biosensors an overview. Measurement
  17. Valenzuela-Amaro HM, Aguayo-Acosta A, Melendez-Sanchez ER (2023) Emerging applications of nanobiosensors in pathogen detection in water and food. Biosensors
  18. Wu L, Yuan X, Tang Y (2023) MXene sensors based on optical and electrical sensing signals. PhotoniX